GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6083804 | chr20:25317060 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.05 | 5.93E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083805 | chr20:25317356 | ENTPD6 | chr20:25176339-25207360:+ | 0.31 | 6.94 | 1.26E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083805 | chr20:25317356 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.41 | 0.000699 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083805 | chr20:25317356 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.52 | 5.64E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083805 | chr20:25317356 | NINL | chr20:25433338-25566153:- | 0.35 | 7.26 | 1.6E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083805 | chr20:25317356 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.73 | 0.000212 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083809 | chr20:25329309 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.29 | 1.31E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083809 | chr20:25329309 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.39 | 0.000746 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083809 | chr20:25329309 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.59E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083809 | chr20:25329309 | NINL | chr20:25433338-25566153:- | 0.34 | 7.13 | 3.83E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083809 | chr20:25329309 | PYGB | chr20:25228706-25278647:+ | 0.17 | 4.21 | 3.08E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083813 | chr20:25337671 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.84E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083813 | chr20:25337671 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000539 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083813 | chr20:25337671 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.08E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6083813 | chr20:25337671 | NINL | chr20:25433338-25566153:- | 0.33 | 6.89 | 1.74E-11 | Liver enzyme levels (alkaline phosphatase) |